Jacquet A, Grolleau A, Jove J, Lassalle R, Moore N
GLP-1, or Glucagon-like Peptide-1, is a hormone produced in the gut, specifically by the L cells of the small intestine and colon
Most evidence comes from standard therapeutic doses used for diabetes or obesity management
This triggers a Medicare funding warning which legally requires the President to submit a proposal to Congress to reduce that dependency
When the Breakthrough Obesity G-Agonist Drugs Exceed Expectations The expanding GLP-1 family of drugs and their expanded potential use cases Back last December I wrote about the The New Obesity Breakthrough Drugs, and specifically the striking results in randomized trials for semaglutide (Wegovy) and tirzepatide (Mounjaro) for weight loss, their putative mechanism(s), while also emphasizing their very high cost, lack of plan for successful weaning, and exacerbation of health inequities
Mounjaro: Mounjaro contains tirzepatide, the first dual GIP and GLP-1 receptor agonist