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Studies have shown that individuals with low B12 levels may experience fatigue, brain fog, and mood changessymptoms that often improve with consistent supplementation
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Important caveat: the evidence base for Chonluten is weak
There is a significant body of research, mostly from the 2000s, on the homocysteine-lowering benefits of B12 in patients with end-stage renal disease and who are on haemodialysis (HD), 80100% of whom have elevated homocysteine levels
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