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Efforts to model Dravet syndrome with patient-derived hiPSCs, which carry a deleterious mutation in the Nav1.1 sodium channel, indicate that cultures of telencephalic interneurons carrying this variant have reduced sodium current density and action potential output

Researchers often identify this compound as a powerful growth factor, which explains the heightened interest from clinical entities like the Novus Center and figures such as Quinn Stillson MD

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Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate to severe plaque psoriasis over 52 weeks: a phase III, randomized, controlled trial (ESTEEM 2)

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