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The exposed, charged surfaces of these crystals are thought to promote interactions with phospholipid membranes and serum factors, thereby contributing to the inflammatory response mediated by these crystals
Neuron 104 , 239255.e212 (2019)
Incretin-based GLP-1 therapies have additional effects, e.g., the reduction of glucagon, the slow down of gastric emptying, and inducing the sense of satiety
This is a substantial reduction, especially when compared to the 2.4% weight loss seen in the placebo group
Yu M, Moreno C, Hoagland KM, et al
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