But the researchers who have been through multiple GLP-1 protocols, who have tried semaglutide, tirzepatide, and now retatrutide , will tell you something different
Heres how I explain it to patients: after an injury, your body sends repair crews to the damage site to create new blood vessels, collagen-producing cells, anti-inflammatory signals
The vast majority of people taking semaglutide do not develop allodynia
And that may be the most disruptive force of all
Although a fairly large proportion of patients have reported a number of side effects, particularly at the gastrointestinal level (nausea, vomiting, diarrhoea), these side effects tend to diminish over time and adherence to treatment remains high, with about 5% of patients discontinuing treatment due to side effects
Tirzepatide works by mimicking the actions of incretin hormones , which enhance insulin secretion in response to meals, suppress glucagon release, slow gastric emptying, and promote satiety