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Start with lower doses when stacking
When symptoms do not improve with conservative management, or in severe cases where permanent, irreversible damage is possible with delay in management, surgery may be necessary
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Consequently, its known salutary effect on gastrointestinal lesions, its effect on chronic inflammation lesions such as adjuvant arthritis and its effect as a non-steroidal anti-inflammatory agent in NSAlAs-induced gastrointestinal lesions were simultaneously studied in rats
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