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Numerous studies (135-178) have indicated that GLP-1RAs can reduce oxidative stress, inflammatory responses, apoptosis and mitochondrial dysfunction, improve insulin resistance, and induce myogenic differentiation, thereby showing potential in the treatment of SIM
The GLP1 Receptor Agonist Liraglutide Protects against Oxidized LDLinduced Endothelial Inflammation and Dysfunction via KLF2
These include phentermine, an appetite suppressant that helps reduce hunger and promotes weight loss, and orlistat, which works by inhibiting the absorption of fats in the digestive tract, leading to reduced calorie intake
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L-carnitine challenge studies also showed that APOE had an impact on the production of L-carnitine metabolites associated with vascular dysfunction
