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The reverse transcription reaction was performed by incubation at 25C for 10 min, followed by 120 min at 37C, and heat inactivation at 85C for 5 min

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This GHR upregulation sensitises local cells to circulating GH, potentiating GH-induced JAK2/STAT signalling and stimulating collagen matrix synthesis, IGF-1 production, and fibroblast proliferation providing a mechanism through which BPC-157 engages the GH/IGF-1 axis at the tissue level without altering systemic GH secretion

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Animal studies have shown it to be cytoprotective against known carcinogens

TB-500 provides cell migration, anti-fibrotic effects, and cytokine modulation