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Switch from tirzepatide to semaglutide when Injection site reactions are persistent and bothersome, since semaglutide has dramatically lower injection site reaction rates

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It is possible that combination therapy offers advantages over monotherapy, opening the debate on whether it should always be adopted as first-line treatment, reserved only for a brief initial phase followed by maintenance monotherapy, or applied only in patients who do not respond to monotherapy

K., Lau, R