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Futhermore, 1,25(OH)2D3 has been demonstrated to reduce the expression of matrix metalloproteinase-9 (MMP-9), which plays a crucial role in degrading extracellular matrix components, including collagen, fibronectin, and laminin, as well as tight junction proteins, leading to BBB instability [106]
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All three sets showed an increase in transcription in response to 5OP exposure in comparison with the unexposed control, with the mgtB area showing the highest increase (Fig
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