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Hif1a can either promote or inhibit the transcription of prosurvival genes under different pathological conditions and thus plays a bidirectional role in the regulation of cellular functions and fates (Choudhry and Harris, 2018)
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If you want a deeper look at that idea, our explainer on All About Liposomes is a helpful place to start
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The choroidal glutathione-S-transferase enzymatic activity is increased following treatment of developing rats with dimethylfumarate GSTs form a multigenic family of GSH-conjugating isoenzymes
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