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Secondary site: Near the lateral epicondyle (bony prominence on the outer knee) and the fibular head (the small bump below and to the outside of the knee)
Slower absorption, which may help retain more B12
But the symptoms you're attributing to high B12 are real, and they're worth investigating
CL Answer Which supplements and foods help with gout and which may worsen it
Why Metformin Can Leave You Too Tired to Lose Weight If youve been on metformin for years, for insulin resistance, PCOS, or type 2 diabetes, and youre too drained to walk after dinner, cook at home, or stick with any weight-loss plan, a low vitamin B12 level could be part of why
The mechanistic story emphasizes neurotransmitter system normalization rather than direct receptor agonism
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