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Ultimately, this FOXO4-DRI-mediated mechanism selectively eliminates senescent endothelial cells, which in turn attenuates vascular inflammation and improves endothelial-dependent vasodilation, conferring a significant protective effect on vascular function

Gastric inhibitory polypeptide immunoneutralization attenuates development of obesity in mice

In addition, people with diabetes are at increased risk for developing certain types of cancer

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(Late 2025)

long-acting analogs such as cagrilintide are widely investigated in obesity and metabolic research, frequently alongside GLP-1 receptor agonists