retatrutide glp 3 GLP-3 RETA Retatrutide vs Semaglutide and Tirzepatide:

The observed sex dimorphism in inflammatory cytokines was a particularly intriguing and unexpected observation, which beyond serving as a marker of aging status, could be reflective of the relative increase and decrease in neoplasms, documented in male and female mice, respectively

Semin Cell Dev Biol 2012

For a deeper look at why dose escalation creates problems long-term, read our post on why higher GLP-1 doses don't always produce better long-term results

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Wu L, Olverling A, Huang Z, Jansson L, Chao H, Gao X, Sjoholm A: GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

Hwa is a member of the AAO-HNS Skull Base Surgery Committee