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Epub 2007 Nov 20

The animals were treated according to the european community prescriptions [EU (86/609/EEC)], then cycled and mated with fertile males at proestrous on 120 d of age, with a positive vaginal smear for sperm, the day after proestrous indicating d 0 of pregnancy

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Molecular Mechanism Receptor Targeting : MT1 binds primarily to the melanocortin-1 receptor (MC1R) on melanocytes, the cells responsible for producing melanin