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Intestinal serotonergic alteration together with the increase in proinflammatory cytokines also generates chronic inflammation, resulting in decreased acid secretion, breakdown of the intestinal barrier, decreased expression of enzymes necessary to digest carbohydrates, and alteration of the intestinal adaptive immune system, leading to the appearance of food intolerances and bacterial overgrowth in the small intestine
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Instead, the benefits tend to accrue over several weeks
This key finding is consistent with recent literature, which has demonstrated that acupuncture similarly suppresses ferroptosis in other inflammatory disease models, such as arthritis and sepsis, further corroborating the converging evidence in this field
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