doi: 10.1007/s00210-012-0771-x 83 ParkY.LeeH.LimJ
This work was supported by the Funds of the National Natural Science Foundation of China (82060728), the Guizhou Provincial Science and Technology Department (MS [2025-380], Thousand Talents Program), the Talents of Guizhou Science and Technology Platform [2021]1350-009, the Zunyi Science and Technology Bureau (HZ-2023-173, HZ-2023-09, [2024] No
Because of these combined effects, GHK-Cu is a potent component of skincare products intended to calm and enhance skin health, providing relief from irritation and promoting a clearer, more balanced complexion
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At the concentrations typically found in cosmetic products, systemic absorption through intact skin is considered minimal, and copper toxicity from topical use has not been reported in the published literature