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Semaglutide treatment commenced at 0.25 mg per week for the initial 4 weeks using a pre-filled pen injector, with a fixed-dose escalation every 4 weeks until reaching the maintenance dose of 2.4 mg by week 16 (lower maintenance doses allowed if 2.4 mg was intolerable for participants)
Fatigue, constipation and headaches are also possible
Understanding this "step therapy" requirement can save you months of delays
Therefore, addressing inherent defects in hormone synthesis and receptor responsiveness is crucial
[1] [2] Levothyroxine is recognised as a medicine with a narrow margin between an effective dose and one that causes harm
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