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Ile 12 Using cryo-electron microscopy, Zhang et al found that a cluster of neighboring serines (Ser 14 , Ser 17 , and Ser 18 of GLP-1) form polar interactions with Thr 298 , the backbone oxygen of Trp 297 , and the nitrogen of Arg 299 in GLP-1R
Shah Z, Kampfrath T, Deiuliis JA, Zhong J, Pineda C, Ying Z, et al
doi: 10.3390/ijms24032959
Part Two: Decreasing DHT By Inhibiting 5-Alpha Reductase Review: Three Levers Of DHT Reduction Remember: in order for dihydrotestosterone (DHT) to form, we need all of the following present: Free testosterone 5-alpha reductase Androgen receptors As a result, this gives us three major levers to reduce DHT levels: decrease 1) free testosterone, 2) 5-alpha reductase, and / or 3) androgen receptors
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