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While the small amounts found in multivitamins are typically safe, high-dose chromium supplements may intensify glucose-lowering effects when combined with GLP-1 medications
Diabetes Care 33(2):428433 Eguchi Y, Kitajima Y, Hyogo H, Takahashi H, Kojima M, Ono M et al (2015) Pilot study of liraglutide effects in non-alcoholic steatohepatitis and non-alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN-J)
Published Phase 2 data (NEJM, 2023) showed retatrutide achieving up to 24.2% body weight reduction over 48 weeks and significant hepatic fat reduction, supporting research into obesity, NAFLD/MASH, and insulin resistance models
Continue prioritizing lean proteins and veggies, and avoid fatty foods
Circulating GLP-1 concentrations increased after induced myocardial infarction in a murine model
The American Migraine Foundation notes that IV magnesium appears most effective in patients with migraine with aura, likely because magnesium helps prevent cortical spreading depression the brain signaling wave thought to underlie visual and sensory aura
