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The x-axis shows the CV risk score derived from subjects baseline characteristics in the semaglutide trials

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Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels

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Transparent and Realistic Positioning Perhaps the most important criterion for evaluating what constitutes the best GLP-1 supplement is how companies position their products and set consumer expectations