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The varied success of anti-inflammatory agents suggests that targeting specific inflammatory pathways (like IL-1 or IL-6) or using agents with broad but relevant mechanisms (like colchicine affecting inflammasomes and neutrophil function) may be more effective than general immunosuppression (methotrexate) or targeting single enzymes (darapladib)
Depending on your needs and preferences, you can choose to treat a specific body area or your entire body
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