One moderate interaction to note is that oral B-complex vitamins, including riboflavin, can interfere with the absorption of tetracycline antibiotics if taken simultaneously
Zinc also affects NK cell cytokine production
It is not known whether oral lipoic acid supplementation can slow cognitive decline related to aging or pathological conditions in humans
doi: 10.1177/2042018821997320
However, there are also secondary pharmacology effects due to the diverse actions of these two hormones such that effects on autonomic nerve activity and hepatic glucose production through gut and portal GLP-1, effects on islet hormone secretion and islet inflammation through intra-islet effects, and effects through other mediators apart from GLP-1 (145147)
Persistent vomiting, severe nausea that prevents eating, diarrhea lasting more than a week, or any symptom that significantly impacts your daily functioning requires medical attention and likely a dose adjustment