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Compounded and FDA-approved medications are not interchangeable
Vitamin B12 absorption from food requires several steps: intrinsic factor secretion from gastric parietal cells, acid-dependent release of B12 from food proteins, and physical contact time in the ileum where transcobalamin receptors capture the B12-intrinsic factor complex
Peptides are not illegal to use or own, but as the BBC notes, "they are not approved for human use, so are not subject to the quality controls that govern pharmaceutical manufacturing." In 2023, under the Biden administration, the FDA classified a group of over a dozen peptides as Category 2 substances, which may "present significant safety risks," effectively banning their use
2: Yuan C, Demers A, Silva-Ortiz V, Hasoon JJ, Lee W, Dave K, Amirdelfan K, Burke HW, Christo PJ, Robinson CL
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If youve tried oral supplements without satisfactory results or want a more direct approach to optimizing your B12 levels, these injections provide an efficient alternative to traditional supplementation
