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Kallyope has announced positive results from its Phase 2b study of the companys lead candidate elismetrep, an oral Transient Receptor Potential Melastatin 8 (TRPM8) antagonist being studied for the acute treatment of migraine

The presence of GLP-1 receptor agonists in these products increased the risk of gastrointestinal complications, ileus, bowel obstruction, and NAION, but the manufacturers knew that such information would discourage consumers from buying and withholding this information

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Cells 9 , 2635 (2020)