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More important, their results revealed that ACN can significantly decrease MDA levels which is a biomarker for lipid peroxidation secondary to generation of ROS and reduce inflammation by preventing upregulation of pro-inflammatory cytokines, such as Interleukin 6 (IL-6), Interleukin 1b (IL-1b) and chemokine (C-X-C motif) receptor 2 (Cxcr2) (Wan et al., 2017)

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Clinical studies, including the STEP 1 trial extension, have demonstrated that patients who discontinue GLP-1 receptor agonists often regain a substantial portion of the weight they lost, sometimes within months