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Lucas says

Saaoud F, Liu L, Xu K, et al

The efficacy of TGF- signaling inhibition can potentially be enhanced through these combinations

During early phases of GLP-1 use, when weight loss may be faster, the risk of muscle loss is higher

While the ADA recommends considering a GLP-1 receptor agonist or the addition of mealtime insulin, 3 the AACE/ACE algorithm additionally recommends SGLT-2 inhibitors and DPP-4 inhibitors as potential therapies that can be added to basal insulin, if they are not already incorporated into the medication regimen

The Ozempic Rebound Effect: A big concern for most people is the dreaded Ozempic Rebound effect