The promoting effect of pentadecapeptide BPC 157 on tendon healing. J Appl Physiol 110(3):774780
However, some patients receiving high-dose B12 supplementation or injections may experience adverse reactions, though these relate to the treatment rather than the elevated levels: Possible reactions to B12 supplementation (particularly injections): Skin reactions, including acneiform eruptions or rashes Pruritus (itching) Injection site reactions (with parenteral administration) Rare hypersensitivity reactions Non-specific symptoms such as headaches, dizziness, or gastrointestinal disturbances have been reported by some patients taking B12 supplements, but causality is not well established in clinical evidence
How are the injections done
Phase 3: Maintenance (Weeks 912) Dose: 3.2 mg, 2-3x per week Pulsed administration keeps the repair signal present without turning the protocol into constant stimulation
Extended Duration: The duration of an IV infusion treatment may last longer than it takes to give a B12 energy shot
Some research protocols include 500 to 1000 mg of vitamin C taken 30 to 60 minutes before exercise or peptide administration