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Examples of GLP-1 receptor agonists and related medications include: Wegovy (semaglutide) Mounjaro (tirzepatide) Saxenda (liraglutide) Ozempic (semaglutide) used to treat type 2 diabetes Trulicity (dulaglutide) used to treat type 2 diabetes Do not use Wegovy together with another GLP-1 receptor agonist
It can miss: impurities with similar retention times, peptides that do not absorb well at the detector wavelength, and endotoxin contamination, which requires a separate LAL or recombinant factor C assay
Novo Nordisk slashed the cash-pay price for starting doses of its diabetes and weight-loss shots, Ozempic and Wegovy, in a bold move to boost sales after its lost ground in the GLP-1 market to Eli Lilly and compounders
10.1016/j.ajpc.2024.100679 81 RizzaS.PietrucciD.LongoS.MenghiniR.TeofaniA.PiciucchiG.et al (2023)
It is used for diabetes management and weight loss in overweight or obese individuals