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The chemistry depends on copper coordination and may be influenced by pH, counterions, oxidation and competing chelators
Discontinuing the medication typically reverses dry mouth within 2448 hours, demonstrating that the effect is directly tied to active GLP-1 receptor signaling rather than a permanent change to salivary gland structure
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The Food and Drug Administration (FDA) has approved several GLP-1 medications for type 2 diabetes (such as Ozempic, Victoza, and Trulicity) and weight management (Wegovy and Saxenda)
Your risk for NAION increases if you are over 50, have a small optic nerve cup, or have sleep apnea
Everything else about GLP-1 is just more detail around that main idea
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