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A realistic earliest FDA decision window, assuming Phase 3 confirms the Phase 2 findings, is 2028

Because it works through a different mechanism, LDN may be appropriate for patients whose weight management challenges have inflammatory or autoimmune components rather than purely metabolic ones

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GLP-1 Receptor Distribution: **Brain: Hypothalamus, brainstem (appetite, satiety, nausea signaling) GI tract: Slows gastric emptying Heart: Cardioprotective signaling (modest direct effects

On the other hand, Januvia falls under DPP-4 inhibitor class

For managing Type 2 diabetes, Ozempic shows significant reductions in A1c, but both medications may be effective at promoting weight loss