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Another curative function of the HO-1 is to facilitate the conversion of heme into BV, Fe 2+ and CO in equimolar quantities, thus promoting efficient antioxidant and anti-inflammatory effects [50]
6.2 Targeting lactate production in the TME Due to the central role of lactate in the TME, targeting its production and transport have been proposed as potential therapeutic strategies (207)
Identification and characterization of a novel glutaminase inhibitor
Overall, rather than directly causing MI to worsen, TMAO is more likely to be a biomarker that predicts the prognosis of individuals admitted for MI [33, 65]
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