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Instruct patients to inform their healthcare provider that they are taking XIGDUO XR prior to any surgical or radiological procedure, as temporary discontinuation of XIGDUO XR may be required until renal function has been confirmed to be normal [see WARNINGS AND PRECAUTIONS ]

Jovanovic, V

further large-scale, multicenter, population-based studies are required to corroborate these findings

Rotating injection sites weekly helps prevent lipohypertrophy (fatty lumps at the injection site) and maintains consistent absorption

While these reports do not establish causation, they underscore the challenges associated with widespread use of a medication that remains under investigation

The effects of this can be seen in several major organs (5)