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Samadi, M., Aziz, S

The net result is a compound that addresses energy balance from both sides simultaneously: reducing intake via appetite suppression (GLP-1R + GIPR) and increasing expenditure via thermogenesis and hepatic oxidation (GCGR)

Beyond its immune-related roles, tryptophan is involved in hepatic function, specifically in the synthesis of niacin (vitamin B3), which is essential for energy metabolism and DNA synthesis (Bouma et al., Similar to GWS and ME/CFS, disruptions in purine metabolism are suspected to play a role in the pathophysiology of FM

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