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Real stories: how Mounjaro changes lives Scientific data is important, but sometimes personal experience speaks louder
In SUSTAIN-6, in adults with type 2 diabetes at high cardiovascular risk, semaglutide reduced the same composite to 6.6% versus 8.9% (hazard ratio 0.74, about a 26% relative reduction)
The most significant risk is additive glucose-lowering effects potentially leading to hypoglycemia, especially in patients taking insulin or sulfonylureas alongside tirzepatide
Journal of Alzheimer's disease : JAD (2020)
Hyperkalemia stimulates aldosterone production and aldosterone, in turn, enhances sodium and water reabsorption in exchange for potassium excretion in the distal tubule and collecting duct of the kidney