A triple combination targeting epigenetic dysregulation and apoptotic resistance, comprising iadademstat (LSD1 inhibitor), azacitidine (a hypomethylating agent), and venetoclax (a BCL-2 inhibitor), is under investigation in a phase I trial for acute myeloid leukemia (NCT06357182)
10.1007/s12026-025-09634-5 2 AbelliJ.Mndez-ValdsG.Gmez-HeviaF.BragatoM
It has not been evaluated by the Food and Drug Administration (FDA) and is not intended to diagnose, treat, cure, or prevent any disease or medical condition
Detailed Description BPC-157 , also known as Body Protection Compound-157, is a synthetic pentadecapeptide (15 amino acids) derived from a naturally occurring protein in gastric juice
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Anti-inflammatory effects are often reported within the first week