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Arvat E, Maccario M, Di Vito L, et al

Hydrolytically sensitive peptides such as Sermorelin and AOD-9604 degrade faster and should be used within 23 weeks, while stabilized analogs like Semaglutide and Tirzepatide can retain potency for 46 weeks

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This is a real chemistry question with a specific mechanistic answer, not just a formulation rule of thumb

Back Marks, V (2020) 'The early history of GIP 19692000: From enterogastrone to major metabolic hormone', Peptides , 125, 170276

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