tirzepatide wegovy Oral Pill: FDA-Approved Options F.D.A. Approves New Obesity Drug

Mean glycated hemoglobin (HbA1c) decreased over time from baseline in the 2.510.0 mg ( 2.4%) and 2.515.0 mg ( 1.6%) tirzepatide groups, at week 16 and week 24, respectively, but remained steady in patients receiving placebo

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But it bears mentioning because patients switching from an MAO inhibitor need a minimum 14-day washout period before starting bupropion, and tirzepatide should not be initiated during this transition period when neurochemistry is already in flux