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How Tirzepatide Works: The Dual GIP + GLP-1 Mechanism Per FDA labeling, tirzepatide is an agonist of both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor

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GLP-1 medications can be highly effective for appropriately selected patients, but they are prescription treatments with real side effects, limitations, costs, and unanswered questions