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Second, improvements in IR and glycaemic indices are most apparent in higher-burden phenotypes, particularly in women with impaired glucose tolerance/prediabetes or related metabolic comorbidities, where changes in HOMA-IR, fasting glucose and OGTT profiles are more pronounced and may plausibly reduce periconception metabolic risk
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You can build this cycle without even realizing it
References Albarqouni, L., Moynihan, R., Clark, J., et al
Thats why GLP-1 medications werent designed as a one-time solution
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