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after the FDA lifted a full clinical hold it had placed on the Investigational New Drug Application for PGN-EDODM1

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Keep in mind that, while rare, serious side effects can occur, such as allergic reactions

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10.1016/j.redox.2014.12.011 177 ZilkaO.ShahR.LiB.Friedmann AngeliJ

Since intense oxidative stress leads to severe damage of biomolecules, triggering cell death, it is easily understood that GSH metabolism might be upregulated in tumor cells to protect them from damage of oxidant and even promote cancer cell proliferation and metastasis