Liu et al., 2022)
It should be noted that these findings do not imply that DPP-4 inhibitors are harmful in any way or that GLP-1 drugs are definitely beneficial for brain health. Kornelius also noted that tirzepatide, a dual GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptor agonist, was not evaluated since it was approved after the beginning of the study period.

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headquarters of Novo Nordisk, the Ozempic manufacturer
The brain, which demands enormous amounts of ATP, can become energy-deprived
LR3 has an N-terminal extension that reduces IGFBP binding (long half-life)