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Even before its recent announcement, the FDA has consistently warned patients that compounded products pose a higher risk than FDA-approved medicines, because the FDA does not review compounded drugs safety, effectiveness or quality

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Synthetic versions can be derived from rooster combs or engineered in a lab, and there are a variety of proprietary formulations available

Healthy clients seeking optimization can proceed without formal lab testing, though baseline serum B12 testing is recommended for clients with significant fatigue symptoms

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