The result is increased NAD+ levels, but through conservation rather than supplementation
Mild burning, redness, or a small bump can happen and typically resolves quickly
GLP-1 use is safe and effective with many pre-existing conditions with the exception of the following: Currently pregnant Currently breastfeeding Currently being treated for cancer Active eating disorder Active gallbladder disease Active substance abuse or dependency Type 1 diabetes Bariatric surgery (within the past 18 months) Pancreatitis within the past 6 months, or a history of pancreatiitis caused by taking a GLP-1 Personal or family history of medullary thyroid cancer or MEN syndrome Personal history of Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
It is not approved for human use, clinical treatment, or athletic performance
Thorne Meta-Balance Best for PMS and best for menopause symptoms Photo by Innerbody Research Pros Most ingredients have supportive research for relief of PMS and menopause symptoms Free ground shipping on all orders 60-day satisfaction guarantee Save 10% on subscriptions (20% on three or more products) Free from common allergens Cons Wild yam doesnt have much supportive evidence behind it High per-serving cost, even with subscription discount Thorne has an impressive variety of supplements to suit almost any concern, but our focus in this guide is on its Meta-Balance product, which is intended for balancing hormones and supporting mood
Civil Engineering, UCLA Last updated: July 2026 Human-researched and AI-assisted with full editorial review