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JAMA Netw Open 5(1):e2142078
Adults with a history of pancreatitis, gallbladder problems, or certain gastrointestinal conditions may need additional evaluation before treatment
Una vez absorbida, la LCLT se distribuye por los tejidos perifricos, especialmente hacia el msculo esqueltico, el corazn y el hgado, pero no cruza efectivamente la barrera hematoenceflica
Risk Stratification & Contraindications Patient safety must guide the initiation of GLP-1 therapy, and therapy should be withheld if contraindications are present: Absolute Contraindications: Personal or family history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Cautionary History: Previous pancreatitis or gastroparesis 5
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Protocol Design Personalized dosing, injection schedule, and combination strategy
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