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High TMAO levels were found to induce activation of the nuclear factor-kappa B (NF-B) pathway and increase the expression of proinflammatory genes including those encoding inflammatory cytokines, adhesion molecules, and chemokines (72)

Researchers noticed that the stomach, despite being exposed to acid that would destroy most tissues, is remarkably self-repairing

Talenezhad N, Mohammadi M, Ramezani-Jolfaie N, Mozaffari-Khosravi H, Salehi-Abargouei A

Alternately, betaine (a metabolite of choline) is used as the methyl donor for the methylation of homocysteine to methionine by the enzyme, betaine-homocysteine methyltransferase (BHMT) (1)

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