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Diagnosis typically includes testing for anti-intrinsic factor antibodies (and sometimes anti-parietal cell antibodies)
FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes
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AOD-9604 is typically compounded in bacteriostatic water at 1 to 5 mg/mL and stored refrigerated at 2, 8 degrees Celsius after reconstitution
At the same time, the unfolded peptides can aggregate, forming clumps of misfolded protein
