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This means the gene mutation happened randomly in their lifetime

Acknowledgements This work is funded by the National Natural Science Foundation of China (81530028

MASLD associated with increased alcohol consumption (2050 g/day for females and 3060 g/day for males) is defined as MetALD, 2 and individuals in this population may have previously been diagnosed with alcohol-related liver disease (ALD)

Women of childbearing potential should discuss pregnancy planning, as these medications are not recommended during pregnancy and should be discontinued at least 2 months before a planned pregnancy

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2018 Feb;78(2):275-284