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Furthermore, while the multi-targeted (polypharmacological) mechanisms are advantageous for a complex disease, they complicate the precise attribution of therapeutic effects to specific structural features or isolated pathways, hindering the development of precisely defined therapeutics
Am J Psychiatry 148 : 13011308
18 Tirzepatide Tirzepatide Tirzepatides (Zepbound
But I think there's this open question of like, is there a boogeyman in the closet like that
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