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Effect of GLP-1/GLP-1R on the Polarization of Macrophages in the Occurrence and Development of Atherosclerosis
Stopping GLP-1 therapy in diabetic patients risks not only weight regain but also deterioration of blood sugar control, potentially requiring additional diabetes medications
Lancet Diabetes Endocrinol 11(4):282298 Wyne KL, Nair L, Schneiderman CP, Pinsky B, Flores OA, Guo D, Barger B, Tessnow AH (2023) Hypothyroidism prevalence in the United States: a retrospective study combining national health and nutrition examination survey and claims data
This is true for most research peptides and represents an inherent risk of adopting compounds before full clinical evaluation
However, a number of interactions have been noted: Both excitatory and inhibitory signaling systems may be impacted by DSIP
